Side effects may include high blood pressure, dizziness, hair loss, respiratory tract infections, bronchitis, skin rash, itching, back pain, abdominal pain, indigestion, and diarrhea. Some people have had life-threatening allergic reactions to leflunomide. Some people have severe reactions, including liver injury, skin and nerve problems, interstitial lung disease, and infections. People taking leflunomide should avoid receiving live vaccines.
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