What are the side effects of denosumab injections?

Denosumab injections can lower the level of calcium in your blood, resulting in a condition called hypocalcemia. Physical symptoms of this condition include: cramps, spasms, twitches and numbness near your mouth, toes and fingers. Denosumab injections may also increase your risk for developing a serious infection. This may be the result of how the drug affects your immune system. If you develop an infection, you may experience pain in your abdomen, frequent urination, a burning sensation when you urinate, chills, swollen or red skin and a fever. Denosumab injections can also result in skin irritation. Blisters, dry skin, itching, rashes, redness and peeling are all possible side effects. Occasionally, denosumab injections will also cause osteonecrosis of your jaw, a severe bone disease. Make sure you consult a dentist before using this drug.