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What should I know about certolizumab pegol before taking it?

Certolizumab pegol can compromise a person's immune system, increasing the risk of infection. Using certolizumab can make a person more at risk for tuberculosis, invasive fungal infections, bacterial infections and viral infections and cancer. Let your doctor know about certain medical conditions before using certolizumab including: tuberculosis, hepatitis B, cancer, seizures, psoriasis, congestive heart failure, bleeding disorders, blood or bone marrow problems, fungal infections, multiple sclerosis, diabetes, eye problems, nerve problems or lupus-like syndrome. Certolizumab can have negative interactions with some medications, including anakinra, azathioprine, cyclosporine, cancer chemotherapy drugs or other medications that affect the immune system. You should not receive a vaccine while taking certolizumab. Pregnant and breastfeeding women should discuss with their doctor the risks and benefits of using certolizumab. People who use certolizumab may increase their risk for some cancers, such as lymphomas, particularly if they are young. If you should experience unusual growths or lumps, swollen lymph nodes or sudden weight loss, notify your doctor immediately. Certolizumab can affect the results of certain laboratory tests. Be sure to let your doctor know you are using the medication before any diagnostic testing. This medication makes it more difficult for your blood to clot. Be very careful to avoid any cuts, scrapes or other bleeding injuries or dangerous situations while on this drug. This drug has been linked to the development of lupus-like symptoms. Talk to your doctor if these occur. Report signs of abdominal pain, persistent fever, night sweats, and weight loss to your doctor right away.


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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.