What precautions are there with colchicine?

Your doctor and pharmacist should discuss several precautions of colchicine with you before you take it. These include:
  • Do not take colchicine if you know you are allergic to it or ingredients in the tablets.
  • Make sure you tell your doctor and pharmacist every prescription drug and nonprescription substance you are taking, including vitamins, aspirin or any dietary supplements.
  • Colchicine may have some harmful interactions with other prescription drugs, including any of the macrolide antibiotics like azithromycin (Zithromax), clarithromycin (Biaxin) and erythromycin (E.E.S., E-Mycin), telithromycin (Ketek), antifungal drugs like fluconazole (Diflucan), the cholesterol drugs known as the statins, like atorvastatin (Lipitor), cyclosporine (GenGraf, Neoral, Sandimmune), digoxin (Digitek, Lanoxin), diltiazem (Cardizem, Dilacor, Tiazac), gemfibrozil (Lopid) and antiretroviral HIV medications.
  • Colchicine may not be good to take if you have kidney or liver disease. Talk to your doctor about this.
  • Make sure you tell your doctor about your plans to get pregnant, if you are currently pregnant or if you are breastfeeding. Colchicine might cause harm to a developing baby.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.