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What is onabotulinumtoxinA?

OnabotulinumtoxinA, also known as botulinum toxin type A, is sold under the brand name Botox. Made from the same bacteria that give people the disease botulism, onabotulinumtoxinA works in muscles, blocking the activity of the nerves and is used to treat muscle-related issues. These include eye problems like strabismus (muscles in the eyes making them point in odd directions) and blepharospasm (uncontrollable twitching or blinking in the tightened eyelid muscles), as well as larger muscle spasms in the arms and hands or extreme muscle spasms in the neck (cervical dystonia). OnabotulinumtoxinA is also used to treat extreme underarm sweating. OnabotulinumtoxinA has additional uses in treating some migraines, uncontrollable shaking and additional sweating issues in other parts of the body like the hands. It can also be used to increase flexibility and mobility in children who have cerebral palsy or adults who have had strokes. It is also used for cosmetic purposes to reduce the appearance of wrinkles. OnabotulinumtoxinA is in the drug class of neurotoxins and is given as an injection. The dosing rate and schedule varies depending on the condition. OnabotulinumtoxinA will not cure the condition it is being used to treat, but it should help lessen the symptoms. There is the possibility that onabotulinumtoxinA could cause some symptoms of botulism if it spreads past the treated area. This can result in extreme swallowing and breathing issues which can become life threatening.

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