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What is leflunomide?

Donna Hill Howes, RN
Family Practitioner

Leflunomide (Arava) is a disease-modifying antirheumatic drug (DMARD) that affects the immune system and reduces inflammation. It is taken as daily tablets, often for the treatment of rheumatoid arthritis (RA). It is used mainly with methotrexate for people who do not improve as much or as quickly as expected while taking methotrexate alone.

It is sometimes used to treat psoriasis or psoriatic arthritis but is not FDA approved for these uses. 

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor. 

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