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What drugs may interact with tizanidine?

Tizanidine (Zanaflex) may interact with other medications, including certain antianxiety and antiseizure medicines, tranquilizers, sleeping pills, sedatives and high blood pressure medicines, including verapamil.

If you're taking the antibiotic ciprofloxacin, birth control pills or fluvoxamine (used to treat obsessive-compulsive disorder), make sure your doctor knows before you begin treatment with tizanidine, which relieves muscle spasms caused by multiple sclerosis (MS). Also tell your doctor if you're taking medicines for heartburn or acid reflux, including over-the-counter drugs such as cimetidine and famotidine.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.