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What is collagenase clostridium histolyticum used for?

Rachel Rohde, MD
Orthopedic Surgery

Collagenase clostridium histolyticum is an injectable substance to treat certain types of Dupuytren’s contractures. It has been approved by the FDA, but not every contracture can be treated with this, and as with any procedure, there still are risks involved. The substance essentially dissolves some of the cord chemically, and the cord is released by the physician 24 hours following the injection. These injections are administered only by hand surgeons who have completed additional training in performing this procedure.

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