What are the side effects of tiludronate?

Contact your doctor immediately if you have any of these serious side effects while taking tiludronate:

  • difficulty or pain when swallowing
  • chest pain
  • burning or pain under the ribs or in the back
  • severe bone, joint, or muscle pain
  • new or worse heartburn
  • jaw pain
  • swelling
  • numbness

More common, and less serious, side effects include:

  • diarrhea
  • mild heartburn
  • stomach upset
  • gas
  • constipation
  • mild back or joint pain
  • headaches

Some people using this or similar drugs have developed bone loss in the jaw. Symptoms of this condition are:

  • jaw pain
  • numbness
  • swelling
  • gum infection
  • loose teeth
  • slow healing after gum surgery

People treated for cancer have a higher risk of this condition, known as osteonecrosis of the jaw. Symptoms of an allergic reaction requiring emergency treatment are difficulty breathing, hives, swelling of the lips, tongue, throat or face.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.