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How does Skelaxin (metaxalone) interact with other drugs or foods?

Taking Skelaxin (metaxalone) with any of the following drugs can increase your risk of side effects including drowsiness, confusion, difficulty breathing, or memory loss:

Alcohol
Secobarbital
Phenobarbital
Butalbital
Amobarbital
Pentobarbital
Chlordiazepoxide
Clonazepam
Clorazepate
Alprazolam
Diazepam
Flurazepam
Estazolam
Lorazepam
Midazolam
Triazolam
Temazepam
Hydrocodone
Morphine
Oxycodone
Sleep medications

Taking Skelaxin (metaxalone) with food may increase your risk of side effects. Talk to your doctor or pharmacist about taking Skelaxin (metaxalone) with food.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.