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What should I know about probenecid before taking it?

Probenecid is a prescription medication that treats gout and gouty arthritis by reducing the levels of uric acid in the blood. It does not cure gout, and it is only effective as long as you continue treatment. You should not use probenecid if you have blood problems or kidney stones caused by uric acid. Probenecid may also be unsafe if you have kidney problems, ulcers, a stomach or intestinal disorder, diabetes, glucose-6 phosphate dehydrogenase deficiency or are currently undergoing radiation treatment. Probenecid may affect the results of urine tests, so tell your doctor you are on this medication prior to any laboratory work. Don't take aspirin while taking probenecid; instead, use a substitute such as Tylenol (acetaminophen).

Other medications may also interact with probenecid. These include: aminosalicylic acid, antibiotics, aspirin, cancer chemotherapy medications, clofibrate, dapsone, diflunisal, diuretics, heparin, indomethacin, anxiety medications, nitrofurantoin, oral diabetes medications, pyrazinamide, salsalate and vitamins. Probenecid may be harmful to fetuses, although the benefits of use may outweigh the risks. Talk to your doctor before taking probenecid if you're pregnant or breastfeeding.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.