How long does it take to get pain relief from hyaluronic acid injections?

Dr. Vonda Wright, MD
Orthopedic Surgery
I never guarantee my patients that they're going to see any effect from hyaluronic acid (HA) injections until at least all three weekly shots are done. That said, people respond to these injections differently. Many of my patients say that after the first HA injection, their knees aren't as stiff or swollen. In other patients, it takes a while to feel pain relief. 
Keith Roach, MD
Internal Medicine
Hyaluronic acid injections, also called viscosupplement injections, don't offer immediate pain relief. They generally start working within two to four weeks and reach maximum benefit by eight weeks. Most people who respond well to this type of treatment for knee osteoarthritis find that the pain relief lasts for many months.

Continue Learning about Muscoloskeletal Agent

Could I be allergic to denosumab?
Stacy Wiegman, PharmDStacy Wiegman, PharmD
Some people are allergic to denosumab, a medicine used to treat thinning and weakening bones (known ...
More Answers
Does teriflunomide have any side effects?
Donna Hill Howes, RNDonna Hill Howes, RN
Teriflunomide stays active in a person's body for several days after it is taken and can stay in the...
More Answers
What are the side effects of leflunomide?
Donna Hill Howes, RNDonna Hill Howes, RN
Side effects may include high blood pressure, dizziness, hair loss, respiratory tract infections, br...
More Answers
Should I worry about allergies with Botox?
Dr. Stuart A. Linder, MDDr. Stuart A. Linder, MD
According to Allergan pharmaceuticals, serious and immediate allergic reactions have been reported. ...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.