How does Colcrys interact with other medications or foods?

A large number of other drugs may have an adverse, even life-threatening interaction with Colcrys. If you are taking an antidepressant, antibiotic or antifungal medication, make sure to tell your doctor before taking Colcrys. Medications to lower cholesterol, treat heart or blood pressure conditions, prevent organ transplant rejection and treat HIV/AIDS, can all interact with Colcrys.

Colcrys should not be taken with the following medicines: amprenavir, aprepitant, atazanavir, clarithromycin, conivaptan, cyclosporine, diclofenac, digoxin, diltiazem, erythromycin, fluconazole, fosamprenavir, gemfibrozil, imatinib, indinavir, interferon alfa-2a, isoniazid, itraconazole, ketoconazole, lovastatin, nefazodone, nelfinavir, pravastatin, quinidine, ranolazine, reserpine, ritonavir, saquinavir, tacrolimus, telithromycin and verapamil.

Atorvastatin, bezafibrate, ciprofibrate, clofibrate, digoxin, fenofibrate, fluvastatin and simvastatin may all increase the side effects of Colcrys. Your doctor may advise you to take Colcrys and these medications at different times to minimize side effects.

Don't eat grapefruit or drink grapefruit juice while taking Colcrys, because this can lead to a life-threatening buildup of the drug in your body. Also, avoid alcohol and tobacco while taking Colcrys. Always follow your doctor's or pharmacist's instructions when taking this drug. 

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