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Can children take probenecid?

Children two years of age and older can take probenecid; it is not approved by the Food and Drug Administration (FDA) for use by younger children. Children two to 14 years old may take probenecid to prolong the actions of the antibiotic penicillin. A usual starting dose is 25 milligrams (mg) per kilogram of body weight; this may go up to 40 mg per kilogram per day, divided into four doses a day. No child should ever receive more than 500 mg per dose; a dose higher than that could be dangerous.

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