What are the different treatment for increasing blood flow in MS?

Louis Rosner
The heat box, fever therapies, and blood vessel dilators, called vasodilators, work on the principle of increasing blood flow or decreasing viscosity. Hydergine, amyl nitrite, aminophylline, papaverine, alcohol, diphenhydramine, benzazoline hydrochloride, belladona, and tetraethylammonium are among the many vasodilator drugs tried unsuccessfully over the years in the treatment of multiple sclerosis (MS).

In MS, histamine therapy was widespread for about fifteen years. Histamine is a chemical found in the body that alters the size of the blood vessels. Today we are more familiar with its effective use in treatment of allergies. The first MS trial, in 1944, was heralded as a success. Even though it was uncontrolled, doctors reported recovery in 75 percent of acute attacks and improvement in 46 percent of chronic cases. Later, however, a controlled test showed no improvements.


Circulation stimulants that raise blood pressure were also tested in the treatment of MS. The list of stimulants includes caffeine, alcohol, ephedrine, adrenocortical extract, desoxycorticosterone acetate (DOCA) and neostigmine. In all, forty cases were studied and some appeared to have good results, but no exact statistics were ever furnished.
Multiple Sclerosis

More About this Book

Multiple Sclerosis

Too often, multiple sclerosis is thought of only as "the crippler of young adults." But in fact, 75 percent of all people with MS will never need a wheelchair. In Multiple Sclerosis, Dr. Louis J....

Continue Learning about Multiple Sclerosis Treatment

What to Expect from MS Infusion Therapies
What to Expect from MS Infusion Therapies
Several therapies for multiple sclerosis are delivered with an infusion, where a venous catheter is inserted into a vein and medicine is delivered int...
Read More
Why was the treatment to increase blood flow devised for MS?
Louis RosnerLouis Rosner
Because multiple sclerosis (MS) lesions begin around small blood vessels, researchers once believed ...
More Answers
Should I take medication for multiple sclerosis (MS)?
Medications are available to slow the course of multiple sclerosis (MS). These medications are calle...
More Answers
What Recent Advances Have Been Made in Multiple Sclerosis (MS) Research?
What Recent Advances Have Been Made in Multiple Sclerosis (MS) Research?

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.