Advertisement

Can estriol be used to treat multiple sclerosis (MS)?

A study suggested that treatment with estriol may benefit people with relapsing-remitting multiple sclerosis (RRMS). Treatment with estriol is not a new concept; however, most of the data to date have consisted of anecdotal reports and small clinical trials.

Data have shown that during pregnancy there is a significant reduction in multiple sclerosis­­–related attacks (or relapses). In fact, during one study, the relapse rate in pregnant women dropped 70 percent during the third trimester. It has been proposed that the increased levels of estriol that are present during pregnancy may be responsible for this effect since estriol suppresses the immune system.

While the data from clinical trials are exciting, treatment with estriol is still experimental. Estriol is not approved by the U.S. Food and Drug Administration (FDA) for the treatment of MS. Compounding pharmacies can compound the product, but a prescription from your doctor will be required. Because estriol is not approved by the FDA, it is not likely that insurance companies will pay for the product.

Estriol should not be considered a replacement for any currently approved disease­modifying treatment.

For information on ongoing clinical trials with estriol, talk to your neurologist.

Continue Learning about Multiple Sclerosis Treatment

What to Expect from MS Infusion Therapies
What to Expect from MS Infusion Therapies
Several therapies for multiple sclerosis are delivered with an infusion, where a venous catheter is inserted into a vein and medicine is delivered int...
Read More
How should I manage my medications for multiple sclerosis (MS)?
Shelley Peterman SchwarzShelley Peterman Schwarz
Here are some ways to help you manage your medications for multiple sclerosis (MS): Ask your doct...
More Answers
Can plasmapheresis help treat multiple sclerosis (MS)?
Multiple Sclerosis FoundationMultiple Sclerosis Foundation
A procedure designed to deplete blood plasma (the liquid part of the blood) without depleting the bo...
More Answers
How Have Therapies Changed for Multiple Sclerosis?
How Have Therapies Changed for Multiple Sclerosis?

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.