Advertisement

What tests assess disease progression in multiple sclerosis (MS)?

The following tools are used to assess disease progression in multiple sclerosis (MS):
  • Minimal record of disability (MRD) has two main functions. It is used to help plan and coordinate care for the individual with MS, and to provide a standardized means of recording repeated clinical evaluations for research purposes. The MRD consists of five parts: demographic information, the Environmental Status Scale, the Disability Status Scale, the
  • Incapacity Status Scale, and the Neurological Functional Systems.
  • Kurtzke expanded disability status scale (EDSS) ranges from one to ten. A person with EDSS score of five or lower can walk independently, whereas a person with a higher score requires some assistance with walking or the use of a wheelchair. Although EDSS is a useful measuring tool in many clinical trials, it should not be interpreted as a true measure of disability because it does not consider upper extremity function, fatigue, or cognitive function
  • Scripps Neurological Scale is used to assess the severity of clinical exacerbations (or relapses) in clinical trials.
  • Magnetic resonance imaging (MRI) scans detect new lesions as well as changes in existing lesions that are clinically undetectable, or asymptomatic. MS is a dynamic disease in which there can be a significant accumulation of lesions, even in clinically stable patients. Yet 5 percent of people with MS show no evidence of the disease on MRI.

Continue Learning about Multiple Sclerosis Diagnosis

Getting an MS Diagnosis
Getting an MS Diagnosis
Being diagnosed with multiple sclerosis can be overwhelming. In this video, MS patient Eliz Martin shares the story of her diagnosis, how she stays co...
Read More
What cases require a myelogram test for the diagnosis of MS?
Louis RosnerLouis Rosner
In the past, when signs or symptoms were confined to the spinal cord and no dramatic remission occur...
More Answers
How often is benign multiple sclerosis wrongly diagnosed?
Dr. Jeanne Morrison, PhDDr. Jeanne Morrison, PhD
Doctors are being much more careful to diagnose benign multiple sclerosis (MS) in light of new findi...
More Answers
Can Alternative Therapies Help Manage Multiple Sclerosis?
Can Alternative Therapies Help Manage Multiple Sclerosis?

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.