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What are possible risks of Lamictal?

The primary risk of Lamictal is a very serious skin reaction called Steven's Johnson Syndrome. This can progress to a life-threatening rash called toxic epidermal necrolysis. When the drug was first approved, the rate at which doses were increased was rather aggressive, and this resulted in approximately a 1% incidence of this side effect in adults. More recently, slower dosage adjustments have become the norm, and I think the rate of this side effect is much lower, though data is hard to come by.

It is important to note that children are more likely to develop Steven's Johnson Syndrome and particular caution is needed in this population, but the drug has great utility in this age group and should not be rejected out of hand because of this risk.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.