Does manganese really work?

Spencer D. Kroll, MD
Internal Medicine
Manganese has been proposed as a mineral that could lower cholesterol levels. No quality clinical trials or studies have shown any effect of manganese intake on cholesterol levels. Manganese in high doses can be toxic. It is not recommended that manganese be used as a supplement for people to treat their cholesterol abnormalities.
Manganese supplements are effective for building up levels of manganese in the body. If you have a deficiency in manganese, supplements can help. Its effectiveness in growing and strengthening bones in people with osteoporosis isn't proven conclusively, however. Even less proven is its ability to treat arthritis, premenstrual syndrome (PMS), and anemia (a low number of red blood cells).

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