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What are the side effects of ergotamines?

Donna Hill Howes, RN
Family Practitioner

If you

  • Have basilar migraine or hemiplegic migraine - You should not take dihydroergotamine
  • Have coronary artery disease - You should not take ergotamine or dihydroergotamine
  • Have heart disease - You should not take ergotamines
  • Have severe high blood pressure - You should not take ergotamine. If you have uncontrolled high blood pressure, you should not take dihydroergotamine.
  • Have impaired kidney function or impaired liver function - You should not take ergotamine or dihydroergotamine
  • Have peripheral vascular disease, including severe arteriosclerosis and Raynaud disease - You should not take ergotamine or dihydroergotamine
  • Are pregnant - You should not take ergotamine or dihydroergotamine
  • Are breastfeeding - You should not take ergotamines
  • Take ergotamine - You should avoid grapefruit and grapefruit juice

Ergotamines have not been shown to be effective in older people and should be avoided.

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.