What drugs or foods should I avoid while taking Glucophage?

While taking Glucophage (metformin) to treat your type 2 diabetes, you should avoid drinking alcohol frequently or in large doses. Drinking alcohol can increase your chances of developing a serious side effect called lactic acidosis.

There are no specific foods or medications you should avoid while taking Glucophage. However, some drugs can interact with Glucophage and increase your risks for side effects. Tell your doctor about all your medications (prescription and nonprescription), supplements and herbal remedies before you start Glucophage. Your doctor may monitor you closely, and adjust your doses as necessary, if you take any of the following medications:
  • antihistamines
  • beta-blockers
  • calcium channel blockers
  • hormone replacement therapy or hormonal contraceptives (birth control pills, patch)
  • insulin or other medications for diabetes
  • asthma or cold medications
  • medications to treat mental illness, seizures or nausea
  • thyroid medications
  • morphine
  • ranitidine (Zantac)
  • thiazides
  • diuretics
  • corticosteriods
  • nicotinic acid
  • furosemide
  • nifedipine
  • isoniazid
  • all cationic drugs (those removed from the body through the kidneys), such as amiloride, cimetidine, digoxin, triamterene, procainamide, trimethoprim, quinidine and quinine

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.