What is the prognosis for gangliosidoses?

Children with early infantile gangliosidoses GM1 often die by the age of three from cardiac complications, or pneumonia. Children with Tay-Sachs disease often die by the age of four from recurring infection. Children with Sandhoff disease generally die by the age of three from respiratory infections.
This answer is based on source information from the National Institute of Neurological Disorders and Stroke.

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