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What medications are prescribed for psychosis in veterans?

Antipsychotic medications are prescribed for veterans with psychotic disorders such as schizophrenia. Antipsychotics block the absorption of dopamine in the brain. Patients with psychosis produce too much dopamine, and the medications block the dopamine receptors. Dopamine is a neurotransmitter which, in excess amounts, can speed up nerve impulses so much that they cause psychotic reactions. When nerve impulses are moving too fast, the patient’s thoughts and perceptions are disordered, resulting in hallucinations and delusions.

The first antipsychotic drugs were originally developed in the 1950s. They generally work best on what are called the “positive” symptoms of psychosis, which are the hallucinations and delusions. They are less effective with the “negative” symptoms of flat affect, low energy, and social withdrawal. The following medications have been used to treat psychosis:
  • Risperdal (risperidone)
  • Zyprexa (olanzapine)
  • Clozaril (clozapine)
  • Haldol (haloperidol)
  • Thorazine (chlorpromazine)
  • Prolixin (fluphenazine)
  • Seroquel (quetiapine)
  • Stelazine (trifluoperazine)

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.