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What is the Dopamine Hypothesis?

One of the earliest hypotheses involving brain chemicals and mental illness was the "Dopamine Hypothesis." This hypothesis, which has stood the test of time, is that excessive activity of a neurotransmitter called dopamine leads to psychotic symptoms. The hypothesis has been bolstered by the fact that drugs which block dopamine reduce psychosis (the antipsychotics), while drugs that stimulate dopamine can induce psychosis (cocaine and amphetamines).

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.