What causes stage 4 melanoma?

Honor Society of Nursing (STTI)

Stage 4 melanoma is caused when melanoma progresses and has spread from the skin through the lymph nodes and into other internal organs. When it first develops, it appears that melanoma is caused when there are problems with the DNA that controls skin cells. In people with melanoma, DNA is damaged and causes an overgrowth of skin cells, which results in a cancerous melanoma. Although it's not proven that ultraviolet (UV) light causes melanoma, skin that is exposed to UVA and UVB radiation from sun exposure or tanning beds seems to be most vulnerable to damage. This damaged skin has cancerous growths that then spread throughout the body.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.

Melanoma

The most serious type of skin cancer, melanoma affects the cells that give our skin its color. Although it can spread easily, it is curable when treated early. This cancer forms when the cells that make melanin grow abnormally or do not die when they should. These cells, called melanocytes, are found in our skin’s outer layer. Melanoma typically begins in a mole or birthmark but can form in other tissues with pigmentation, such as your eye. When melanoma develops in the eye, it is called Intraocular Melanoma. Protect yourself by avoiding overexposure from the sun’s ultraviolet rays. Stay vigilant of any changes in your skin, especially if you have the skin disease Xeroderma pigmentosum, which makes you sensitive to light. You are also more likely to develop melanoma if someone in your family has been previously diagnosed with this specific type of cancer.

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