What medical problems may occur when taking Chantix?

Nina Evans
Some people may experience medical problems while taking Chantix (varenicline). Emotional changes can occur, including depression, nervousness and suicidal thoughts. If this happens, stop taking the drug at once and call your doctor.

A rare skin disorder, Stevens-Johnson syndrome, can also occur. This syndrome can start as a skin rash or blistering on your skin, mouth, nose, or eyes; you may have fever and body aches too. If that happens, stop taking the drug immediately and call your doctor. Chantix may also pose risks to people with cardiovascular disease and kidney disease, so if you have either, talk to your doctor.

If you take Chantix (varenicline) for smoking cessation, it's important to see your doctor regularly to check for the following medical problems:

  • changes in mood such as agitation and irritability
  • depression
  • suicidal thoughts or tendencies
  • allergic reactions such as swelling of the tongue, mouth, ear lobes, face and throat
  • hives, itching, blistering, peeling of the skin
  • skin ulcers or sores
  • difficulty breathing, chest tightness, cough, wheezing
  • fever, chills
  • dizziness, difficulty concentrating
  • a possible increase in heart attacks and heart-related events in people who have cardiovascular disease

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.