What is buprenorphine HCl and naloxone HCl?

Stacy Wiegman, PharmD

Pharmacy

Buprenorphine HCl and naloxone HCl (sold under the brand names Suboxone and Subutex) is a combination drug that is used to treat dependence to opiate drugs, such as heroin and oxycodone. Buprenorphine HCl is an opioid partial agonist-antagonist, which means that the drug binds to specific receptors in the brain to reduce the euphoria associated with taking opiates. Naloxone HCl decrease symptoms of withdrawal, allowing cessation without potentially harmful withdrawal symptoms. This combination medication should be prescribed by a physician, and should also be part of a narcotic-dependence treatment plan.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.

Dependency Agent

Medications are an important treatment for patients who are trying to stop their dependencies on alcohol, tobacco, opioids and other substances. These medications suppress withdrawal symptoms and prevent relapse and are effective when combined with counseling.

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