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What should I know about naltrexone before taking it?

Before taking naltrexone, you should provide your doctors with your complete medical history, including any medications or supplements you are taking, and any medical conditions you have or have ever had. It is especially important to notify your doctors if you have or have ever had hepatitis, liver disease, or kidney conditions. When taken in large doses, naltrexone can cause liver disease. It is also important to notify a doctor if you have a history of depression or suicidal thoughts.

You may experience symptoms of withdrawal from opioid medicines while taking naltrexone. Only individuals who have stopped using drugs and alcohol should use naltrexone. Individuals who have used drugs or alcohol within the prior 10 days should notify a doctor before using naltrexone. It is important to tell your doctor if you are breast-feeding, pregnant, or plan to become pregnant, so that you and your doctor can weigh the potential risks against benefits of taking naltrexone. Other medications may interact with naltrexone, especially opioid medications, methadone, narcotic analgesics, narcotic cold and allergy medications, and diarrhea medications.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.