Can Chantix cause changes in mood?

Nina Evans
Chantix (varenicline) can cause changes in mood. Some people say they feel depressed, hostile, nervous, and even suicidal while taking Chantix. We don't know whether the drug itself is causing these mood changes, or if nicotine withdrawal is the culprit, but you should pay attention to how you feel when you take Chantix. Ask your friends and family to keep an eye on you and tell you if they notice that your attitude or behavior has changed. If you experience any mood changes, stop taking varenicline and call your doctor right away.

The Food and Drug Administration (FDA) requires that Chantix (varenicline) carry a warning that mood changes may occur in people taking Chantix to quit smoking. The warning mentions the following mental problems associated with Chantix:

  • Extreme neuropsychiatric problems such as depression, suicidal thoughts and attempted suicide.
  • Exacerbation of underlying mental health illnesses.
  • Neuropsychiatric symptoms, including mood swings, psychosis and hostility.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.