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What causes pulmonary alveolar proteinosis?

Pulmonary alveolar proteinosis (PAP) is an uncommon lung disease that ranges from mild to severe. The cause of PAP is a defect in the recycling and breakdown of surfactant, an important lubricant found in pulmonary cells. Surfactant abnormally accumulates within the air sacs of the lungs. This results in less oxygen exchange in the lungs and difficulty breathing and hypoxia.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.