What is large cell undifferentiated carcinoma?

Large cell undifferentiated carcinoma is a subtype of non-small cell lung cancer (NSCLC) responsible for about 15 percent of lung cancer cases. Large cell undifferentiated carcinoma is named for the cells that comprise it: the cells are large with large nuclei, and the corresponding tumors are large with areas of necrotic tissue. Large cell undifferentiated carcinoma is linked with smoking, grows quickly, and is known to spread early. Unfortunately, this type of cancer has a poor prognosis.

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