What drugs interact with eszopicline (Lunesta)?

Donna Hill Howes, RN
Family Practitioner

If you are using azelastine nasal spray, conivaptan, idelalisib, orphenadrine, paraldehyde, sodium oxybate, or thalidomide, eszopiclone can lead to side effects and should be avoided.

If you are taking a central nervous system depressant, rufinamide, or a selective serotonin reuptake inhibitor, eszopiclone may not be a good option for you.

If you take eszopiclone, you should avoid kava kava.

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor.

Continue Learning about Insomnia

How can I cope with insomnia during pregnancy?
Diana MeeksDiana Meeks
During week 15, many women start to experience varying degrees of insomnia. Leg cramps and the need ...
More Answers
What should I include in my diet if I have insomnia during pregnancy?
Dr. Mehmet Oz, MDDr. Mehmet Oz, MD
If you have insomnia, you should already be limiting caffeine and not drinking alcohol during yo...
More Answers
What can I do to manage my insomnia?
Diana MeeksDiana Meeks
If you have chronic insomnia, you may want to talk to your doctor about treatment options. Follow th...
More Answers
How common is insomnia?
Katie LoganKatie Logan
Women are twice more likely to suffer from insomnia than men. Some research suggests that certain so...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.