There are two prime contenders for the title of the worst pandemic in human history - The bubonic plague of 14th Century Europe and the Spanish flu pandemic of 1918. The Spanish flu pandemic is estimated to have affected roughly 500 million people and caused 20 million to 50 million deaths worldwide between 1918 and 1920--more than World War I. The bubonic plague killed as many as 50 million people, possibly 60 percent of the population of Europe, beginning about 1346.
- Q Are there any historical pandemic diseases that no longer exist?
- Q What could cause a historical-type pandemic today?
- Q What is a pandemic?
- Q What are the chances of another pandemic?
- Q Are all pandemics infectious in nature?
- Q Why do infectious disease pandemics have high mortality rates?