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What is natalizumab?

Donna Hill Howes, RN
Family Practitioner

Natalizumab (Tysabri) is a manufactured antibody that prevents certain immune cells from attacking and harming brain tissue. It is given as a monthly intravenous (IV) infusion. It is sometimes prescribed for people with relapsing-remitting multiple sclerosis (MS) who can't take other drugs or when other drugs don't work. It may also be prescribed for people with a very aggressive form of MS.

Because it can cause a very serious condition called progressive multifocal leukoencephalopathy (PML), this drug is only available through the TOUCH Prescribing Program. People must be enrolled in this program before natalizumab can be prescribed. Your doctor can help you enroll and can contact the TOUCH Prescribing Program at (800) 456-2255. 

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor. 

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.