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How effective are TNF inhibitors for treating rheumatoid arthritis?

Donna Hill Howes, RN
Family Practitioner

TNF inhibitors act quickly to slow or stop joint damage from RA. Most studies compare people treated with a TNF inhibitor plus methotrexate to people taking only methotrexate. These studies show reduced pain and disability, fewer tender or swollen joints, and lower levels of C-reactive protein in the blood, which suggests lower levels of inflammation. Improvements are also seen on joint x-rays.

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