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Do tumor necrosis factor inhibitors have any side effects?

Donna Hill Howes, RN
Family Practitioner

Side effects may include headache, high blood pressure, high cholesterol, inflamed throat or sinuses, skin rash, indigestion, nausea, abdominal pain, blood in the urine, joint pain, and jaundice. Some people have skin reactions where the drug is injected.

TNF inhibitors increase the risk for serious infections with bacteria, viruses, and fungi. People with active infections should not start taking TNF inhibitors. Live vaccines should not be given while taking TNF inhibitors. Some people have serious, even fatal, reactions to these drugs, such as liver failure, reactivation of chronic hepatitis B, blood and autoimmune disorders, lymphoma, skin cancers, and a systemic allergic reaction following an injection. 

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.