Are there any risks in taking rabies immune globulin?

The risks of receiving rabies immune globulin are somewhat minimal compared with the benefit that comes with preventing the onset of rabies infection, an incurable disease. The most prominent risk is allergic reaction, especially if you suffer from immunoglobulin A deficiency. Pregnant women also may be taking a risk, but that risk is as yet not known, due to lack of human trials. Rabies immune globulin is derived from human plasma and has been treated to destroy any possible infectious elements.