People with G6PD deficiency don't show symptoms until their red blood cells begin to break down, a process called hemolysis. At that point, they display symptoms of hemolysis, not of the deficiency itself. These side effects include fever, paleness, dark-colored urine, yellowish skin (a condition called jaundice), general tiredness, and increases in both heartbeat and the rate of breathing. A physical exam might also reveal that the spleen has become larger.
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Reston Hospital Center answered
Most people don’t have noticeable symptoms, meaning it does not usually interfere with everyday life. Some people can have hemolytic anemia (where the red blood cells are destroyed and not reproduced), they can be pale (in people of dark skin, it’s mostly around the mouth, lips or tongue), extreme tiredness, rapid heartbeat along with rapid breathing or shortness of breath, jaundice (yellowing of the skin and eyes), dark colored urine. If the spleen is checked, it can be enlarged.
These are the most common symptoms, if you end up having symptoms. Always remember to have your symptoms evaluated by a medical professional.