Hormone replacement for congenital hypogonadism involves taking increased levels of testosterone, estrogen, or pituitary hormones. The specific hormone will depend, of course, on the specific case: male or female, primary or secondary cause. Women will sometimes be given both estrogen and testosterone, the latter to increase sex drive. Progesterone is also usually prescribed with estrogen for women who still have their uteruses, as long-term estrogen therapy can lead to endometrial cancer. Although estrogen can be taken in pill form, testosterone generally isn't, as it can cause liver damage and heightened cholesterol levels.
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