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What should I know before taking lomitapide?

Donna Hill Howes, RN
Family Practitioner

Because lomitapide can cause liver damage, it is available only through a restricted program. You must qualify for treatment in order to receive the drug. You will also need to have your liver enzymes measured before starting treatment. Women of childbearing age will need a pregnancy test. (If you are pregnant, you should not take lomitapide.) If you take lomitapide, you should limit alcohol consumption to 1 drink per day.

If you are breastfeeding, you should not take lomitapide.

If you have mild liver function impairment, lomitapide may not be a good option for you. If you have moderate to severe liver function impairment, you should not take lomitapide.

If you have impaired kidney function, lomitapide may not be a good option for you. 

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.