Advertisement

Does lomitapide cause any side effects?

Donna Hill Howes, RN
Family Practitioner

Side effects may include fatigue, fever, headache, dizziness, nasal congestion, nose and throat inflammation, weight loss, back or chest pain, angina, palpitations, indigestion, acid reflux, diarrhea, nausea, vomiting, abdominal pain or bloating, constipation, flatulence, and a strong urge to defecate. Over 90% of people taking lomitapide experience gastrointestinal problems, which may be severe.

Lomitapide can raise liver enzyme levels and cause fatty liver, increasing the risk for liver disease. Lomitapide reduces the absorption of fat-soluble vitamins (A, D, E, and K). Supplements of these vitamins are recommended when taking lomitapide. Lomitapide contains lactose. People with inherited galactose intolerance or problems absorbing glucose-galactose may have diarrhea and malabsorption.

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor.

Continue Learning about High Cholesterol

Good Fats = Good Cholesterol
Good Fats = Good Cholesterol
Avocados, nuts, olives and seeds—even if you have high cholesterol, don't give 'em up. In case you haven't quite gotten the whole good-fats-versus-ba...
Read More
Does mipomersen interact with any other medications?
Donna Hill Howes, RNDonna Hill Howes, RN
If you are taking lomitapide, mipomersen can lead to side effects and should be avoided. If you are...
More Answers
What are PCSK9 inhibitors?
Donna Hill Howes, RNDonna Hill Howes, RN
PCSK9 (Proprotein Convertase Subtilisin Kexin 9) inhibitors help the liver clear LDL cholesterol fro...
More Answers
What are the cholesterol lowering medications?
TriStar Horizon Medical CenterTriStar Horizon Medical Center
The most common cholesterol lowering medications are called statins. Statins work by slowing down th...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.