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Stacy Wiegman, PharmD, Pharmacy, answeredThe best way to take curcumin depends on the condition it is being used to treat. As an oral treatment, it is absorbed by the intestines somewhat more effectively as a pill or an extract. If curcumin is being used to treat a skin condition like scabies, it should be applied topically in combination with the herb Azadirachta indica. You should also know that herbs and supplements, such as curcumin, are not regulated by the U.S. Food and Drug Administration, and should always be used with caution and under a doctor's supervision. Research is still underway to determine the safety and effectiveness of curcumin.