Advertisement

How effective are daclatasvir and sofosbuvir?

Donna Hill Howes, RN
Family Practitioner

Daclatasvir and sofosbuvir has been reported to lower viral load within 12 weeks in over 90% of people with hepatitis C. This combination appears equally effective for people with genotype 1, 2, 3, or 4, people who also have HIV infection, and people who have not responded to telaprevir or boceprevir.

In one study, daclatasvir taken with sofosbuvir for 12 weeks lowered hepatitis C (HCV) viral load in 97% of people with both HCV and HIV infections. This study included people who had been treated for HCV before, as well as people who had not. Most of the people in the study had virus genotype 1, but treatment was about equally effective for all genotypes.

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor. 

Continue Learning about Hepatitis C

Hepatitis C and Diabetes Risk
Hepatitis C and Diabetes Risk
It’s estimated that over 70 million people in the world have hepatitis C, a chronic viral infection that causes inflammation in the liver. This infect...
Read More
What are some complications from hepatitis C?
Univ. of Nev. School of Medicine, Family MedicineUniv. of Nev. School of Medicine, Family Medicine
Most people with hepatitis C don't have any symptoms. If symptoms do appear, they can be a sign of s...
More Answers
The Best and Worst Foods for Hep C
The Best and Worst Foods for Hep CThe Best and Worst Foods for Hep CThe Best and Worst Foods for Hep CThe Best and Worst Foods for Hep C
Find out which foods you should (and shouldn't) eat with hepatitis C.
Start Slideshow
Is Hepatitis C Treatable?
Is Hepatitis C Treatable?

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.