How effective are sacubitril and valsartan in treating heart failure?

Donna Hill Howes, RN
Family Practitioner

The large study that led to the approval of Entresto was stopped early because early results showed strong benefits. The combination was compared to enalapril, which itself is a highly effective heart failure treatment. People taking sacubitril + valsartan had significantly lower rates of hospitalization for heart failure and death due to cardiovascular causes than those taking enalapril. People in both groups were also taking other recommended heart failure drugs.

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor.

Continue Learning about Heart Failure Treatment

What is digitalis?
Discovery HealthDiscovery Health
The use of digitalis as a treatment for heart failure was first described in 1785, when it was disco...
More Answers
How effective is ivabradine?
Donna Hill Howes, RNDonna Hill Howes, RN
A higher heart rate is linked with a higher risk of worsening heart failure. Ivabradine helps lower ...
More Answers
How do I prepare for a cardioversion?
Intermountain HealthcareIntermountain Healthcare
Here's how you can prepare for cardioversion:Take anticoagulant medication if your doctor prescrib...
More Answers
What Are the Treatment Options for Heart Failure?
What Are the Treatment Options for Heart Failure?

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.