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What is Unituxin?

Unituxin is a brand name for dinutuximab, a drug used to treat high-risk neuroblastoma, which is a cancer of the nerve cells. Neuroblastoma almost always occurs in children under 10 and infants. Unituxin bonds to the surface of cancer cells and breaks them down. It is administered as an IV infusion over 10-20 hours, over four consecutive days. More than a quarter of patients may suffer severe infusion reactions including very low blood pressure or breathing problems, or life-threatening allergic reactions; Unituxin patients are carefully monitored and given medication before treatment to help prevent these. Unitixin also is known to cause neuropathic pain, or pain of the nerve pathways; IV opioid painkillers are also given to prevent or ease this severe pain. It can also lead to an increased risk of infections. Unituxin should not be used in pregnancy. Other side effects include nausea, vomiting, low electrolytes, anemia, and fever. 

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