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How does the PCOS phenotype improve as women age?

Daniel A. Dumesic, MD
Reproductive Endocrinology
As testosterone drops as women age, not surprisingly, the polycystic ovary syndrome (PCOS) phenotype improves. The reason: for every decade that women age from puberty to late reproductive life, the number of follicles in their ovaries decreases. As their follicle numbers decrease, so do their testosterone levels. So while a young woman has around an 80% chance of a severe PCOS phenotype, by the time she is in her 30s, the incidence of a severe phenotype drops to 72% and the mild form increases to 17%.

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