What precautions are there for darifenacin (Enablex)?

Darifenacin (Enablex) has precautions that your doctor should discuss with you. These include:
  • Do not take darifenacin if you know you are allergic to it or any other overactive bladder drug. If you don't know for sure, talk to your doctor.
  • Make sure you tell your doctor all prescription drugs and nonprescription substances you are taking, including vitamins, aspirin or any dietary supplements. Darifenacin may interact with tricyclic antidepressants, such as amitriptyline; the antidepressant nefazodone (Serzone); antihistamines, such as diphenhydramine (Benadryl); antibiotics such as clarithromycin (Biaxin); and other drugs, such as flecainide (Tambocor), ipratropium (Atrovent), itraconazole (Sporanox) and other antifungals; medications for irritable bowel disease, such as dicyclomine (Bentyl); and medications for motion sickness, Parkinson's disease, ulcers or urinary problems, and some HIV/AIDs medications, such as nelfinavir (Viracept) and others.
  • Make sure to tell your doctor about any previous problems with urinating, including any urinary or gastrointestinal obstruction, enlargement or inflammation of the prostate (benign prostatic hypertrophy), constipation, any inflammatory bowel problem, such as ulcerative colitis or Crohn's disease, the neurological condition myasthenia gravis, liver disease or glaucoma (pressure in the eye).
  • Make sure to tell your doctor about your plans to get pregnant, if you are currently pregnant or if you are breastfeeding. Darifenacin might cause harm to a developing baby.
  • Darifenacin may cause dizziness or blurred vision, so do not operate machinery or drive a car until you know if the medication is safe.
  • Darifenacin may cause you to sweat less, which could cause you to overheat in warm or hot temperatures.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.