Advertisement

What are the “Amsterdam criteria”?

The Amsterdam criteria are a system doctors use to determine if you should seek genetic counseling for hereditary non-polyposis colorectal cancer (HNPCC) and familial adenomatous polyposis (FAP). If these hold true for your family, then you might want to seek genetic counseling. But even if your family history satisfies the Amsterdam criteria, it doesn't always mean you have HNPCC. Only about half of families who meet the Amsterdam criteria have HNPCC. The other half do not, and although their colorectal cancer rate is about twice as high as normal, it is not as high as that of people with HNPCC. On the other hand, many families with HNPCC do not meet the Amsterdam criteria. The Amsterdam criteria are:
a. At least 3 relatives have colorectal cancer
b. One should be a first-degree relative (parent, sibling, or child) of the other 2 relatives
c. At least 2 successive generations are involved
d. At least 1 relative had their cancer when they were younger than the age of 50
 

Continue Learning about Genetic Disorders and Birth Defects

After a stem cell transplant, why is it important to avoid public places?
Jumo HealthJumo Health
After a stem cell transplant, it is important to avoid public places because the transplant leaves t...
More Answers
How long does it take to recover after a stem cell transplant?
Jumo HealthJumo Health
It can take between three months and one year to recover from a stem cell transplant. During this ti...
More Answers
Do children with CF have to eat more food than children without CF?
Jumo HealthJumo Health
Children with cystic fibrosis (CF) have to eat more food than their friends without CF to make sure ...
More Answers
Why is it so difficult to find a donor for a stem cell transplant?
Jumo HealthJumo Health
It can be difficult to find a donor for a stem cell transplant because not all stem cells are the sa...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.