What is Peutz-Jegher’s syndrome?

People with Peutz-Jegher’s syndrome (a rare inherited condition) tend to have freckles around the mouth (and sometimes on the hands and feet) and large polyps in their digestive tracts. They are at greatly increased risk for colorectal cancer, as well as several other cancers, which usually appear at a younger than normal age.

Identifying families with these inherited syndromes is important because it allows doctors to recommend specific steps, such as screening and other preventive measures, at an early age.

Several types of cancer can be linked with these syndromes, so it's important to check your family medical history for polyps or any type of cancer. If you have had adenomatous polyps or cancer, it's important to tell your close relatives. People with a family history of colorectal polyps or cancer should consider genetic counseling to review their family medical tree and determine whether genetic testing may be right for them. If needed, this can help them decide about getting screened and treated at an early age.

Continue Learning about Genetic Disorders

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.