What causes Fabry disease?

Diana Meeks
Diana Meeks on behalf of Sigma Nursing
Family Practitioner

Fabry disease is an inherited condition caused by an absence or decreased amount of a specific chemical known as α-galactosidase A. When this chemical is normally produced by the body it helps break down a substance called globotriacylceramide, also known as GL-3. When a person lacks the chemical or enzyme, GL-3 builds up in the tissues of the body causing many progressive health problems.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.